Neoadjuvant treatments for triple-negative breast cancer (TNBC)
نویسندگان
چکیده
منابع مشابه
Neoadjuvant treatments for triple-negative breast cancer (TNBC).
Neoadjuvant chemotherapy provides a means both of improving subsequent surgical intervention and of testing novel therapies or combinations. Historically, triple-negative breast cancer (TNBC) has responded well in the neoadjuvant setting, with rates of pathological complete response (pCR) commonly higher than for other breast tumour types. However, more than half of TNBC patients do not achieve...
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The absence of drug-targetable receptors in triple-negative breast cancer (TNBC) makes the use of targeted systemic therapy inappropriate for this breast cancer subgroup. Although patients with TNBC show sensitivity to some chemotherapy regimens, in early-stage disease greater emphasis is placed on locoregional treatments, based on surgery and radiation therapy (RT). Ongoing improvements in bot...
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Breast cancer is a big challenge for universal public health and has made as nuisance for every people who suffered from this disease. It is the second most common cause of cancer-related deaths in women worldwide. Triple-negative breast cancer (TNBC) is an advanced multi-drug resistance (MDR) breast cancer which affect majority of women worldwide Bakrania et al. [1]. TNBC is distinct by the la...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2012
ISSN: 0923-7534
DOI: 10.1093/annonc/mds193